Single Gene Diagnosis (PGD)

Preimplantation genetic diagnosis (PGD) is a diagnostic test performed with in vitro fertilization (IVF), to find out if the embryo(s) have genetic diseases or chromosomal abnormalities. PGD is the most established advancement in genetic testing to ensure babies are born without genetic abnormalities or diseases. Couples with a family history of serious genetic disorders, or who carry a genetic disease themselves, have successfully decreased the likelihood of having a child with these serious conditions.

PGD Procedure
PGD combines two procedures available at our center:

  1. In vitro fertilization (IVF)
  2. Genetic analysis of a cell from each embryo in order to identify genetic disorders: The process begins when a single cell is removed from an embryo and tested for genetic problems. This complex testing identifies embryos with common genetic complications. By transferring only non-affected embryos to the mother’s uterus, the probability that couples will have a healthy child increases greatly. PGD does not test for every chromosome or genetic defect. PGD is not automatically part of a conventional IVF cycle. This specialized testing must be specifically requested by the patient or recommended by the physician.

Indications for PGD
PGD is recommended for patients who are at risk for serious genetic disorders such as cystic fibrosis, sickle cell disease, or Down’s Syndrome. PGD is also helpful for patients with unexplained infertility, recurrent miscarriages, unsuccessful IVF cycles, advanced maternal age, or male factor infertility. In large studies of miscarriages, the genetic defect rate ranges from 50% -80%.

To learn more about Single Gene Diagnosis  schedule a consultation by filling out the form to the right or call (702) 262-0079

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